Amidst the things I do the target who I'm engaging with is after I've determined their in my niche interest i the use the Mr.
Tweet firefox plugin. It tells me the of tweets they send out a day, the percentage of conversations they have on the top of the of links,. That's right! I don't waste my time with them since This takes a little more work when looking for people the engage with me it lets me know right off the bat if they are just spreading links and zero engagement. From that point I'm able the engage in real world communication. RT's direct communication is a good start.
We keep our eyes on other educational entities that we admire, as a non profit educational publisher. This allows us the remain focused on our mission and find people with like mindedness the actually build relationships with. Eventually, what great timing! We are having a meeting on our burgeoning Twitter strategy in a few hours.